Pathogenic effector TH2 lymphocytes in human nasal polyposis
نویسندگان
چکیده
منابع مشابه
Pathogenic Effector Th2 Cells in Allergic Eosinophilic Inflammatory Disease
There is an absolute requirement for Th2 cells in the pathogenesis of allergen-driven eosinophil-rich type 2 inflammation. Although Th2 cells are generally regarded as a homogeneous population, in the past decade there has been increasing evidence for a minority subpopulation of IL-5+ Th2 cells that have enhanced effector function. This IL-5+ Th2 subpopulation has been termed pathogenic effecto...
متن کاملGenetics in Nasal Polyposis
1Department of Allergy, University Hospital of Salamanca, Salamanca, Spain 2Department of Clinical Biochemistry, University Hospital of Salamanca, Spain 3Department of Medicine, University of Salamanca, Spain 4Department of Genetics, University of Salamanca, Spain 5Centro de Investigación Biomédica en Red en Enfermedades Respiratorias (CIBERES) and Allergy Unit, Hospital Clínic, Barcelona, Spai...
متن کاملSalicylate Food Intolerance and Aspirin Hypersensitivity in Nasal Polyposis
Background: A clear association between allergy and nasal polyposis (NP) is not determined and the role of food intolerance in patients with NP is not investigated by oral food challenge (OFC). Objective: To investigate the relation of salicylate food intolerance and atopy in patients with NP according to recurrence and aspirin sensitivity. Methods: A cross sectional multicenter study was d...
متن کاملManagement of nasal polyposis.
These guidelines are modified from the recent EAACI Position Paper. Nasal polyposis is characterized by an inflammatory process, the factors of which are summarized. Recently, Staphylococcus aureus enterotoxins have been identified to modify the disease. A classification system for polyps, grading systems and epidemiologic data are given, frequent comorbidities are discussed. The diagnostic man...
متن کاملFungal sensitization in nasal polyposis.
BACKGROUND There are indications that polyposis is somehow related to allergic phenomena. Fungal sensitization in substantial proportions of patients has been cited as a trigger of inflammatory mechanisms involving either an immunoglobulin (Ig) E-mediated reaction to fungal colonization or fungal invasion of tissues. OBJECTIVE To confirm whether fungi were involved in the development of polyp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2019
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2018.12.651